Description
RNA is an incredibly versatile biological macromolecule whose function is carried out not only on the level of its primary sequence of nucleotides, but also by the local and global structures that are created when the constituent nucleotides form base pairs. Many RNA structures are thus involved in translational control, RNA localization, gene regulation, RNA stability, and more. Furthermore, in a large number of bacterial, plant, animal, and human viruses, positive-strand RNA takes on the role of their genomes. Far from simply coding for the protein pr
oducts, both local structural elements as well as long-range structural interactions in the genomes of RNA viruses are involved in many fundamental viral processes such as virus disassembly, translation, genome replication, and packaging, and are thus in general important for viral fitness.
Aim
The aim of the workshop is to bring together researchers working on various aspects of RNA structure, topology, and function from both theoretical and experimental point of view, with a special focus on the genomes of RNA viruses.
Invited speakers
- R. Amit, Technion
- G. Bussi, SISSA
- M. Comas-García, Universidad Autonóma de San Luis Potosi
- M. Hagan, Brandeis University
- M. Marz, Friedrich-Schiller-University Jena
- C. Micheletti, SISSA
- K. Roeder, University of Cambridge
- B. Sargueil, Université Paris Cité
- R. Smyth, Helmholtz Institute for RNA-based Infection Research
- G. Stirnemann, Université de Paris
- M. Szachniuk, Poznan University of Technology
- J. Trylska, University of Warsaw
- R. Twarock, University of York