From Hadrons to Therapy: Fundamental Physics Driving New Medical Advances

Session

Enhancing radiotherapy by means of nanotechnology

8 Sept 2022, 16:00

Aula Leonardi (ECT*)

Conveners

Enhancing radiotherapy by means of nanotechnology

• Francesco Giuseppe Cordoni (University of Trento, Trento, Italy)

12. Experimental and computational studies of nano-structured gold as a radiosensitizer for proton and carbon ion radiation

Jefferson Shinpaugh (East Carolina University, Greenville, USA)

08/09/2022, 16:00

Radiation sensitisers and enhancers

Nanostructured materials are widely being studied as radiosensitizers to increase the efficacy of radiation therapy in the treatment of cancer. Here we present recent results for enhanced cell killing for in-vitro irradiation by protons of malignant prostate and breast epithelial cells treated with gold nanoparticles in an energy range approaching the Bragg peak.Theexperiments were conducted...

2. Track structure simulations in nano sized geometries

Michael Dingfelder (East Carolina University, Greenville, USA)

08/09/2022, 16:40

Modelling of radiation propagation, effects and radiobiology

Monte Carlo (MC) radiation transport codes for charged particles, including electrons, protons, light and heavy ions, provide detailed information about interaction types, spatial and temporal distributions of energy depositions, as well as radical species produced in the early physical and chemical states of radiation action with matter. This information allows to investigate the biological...